|
|
  |
|
         |
 |
 |
 |
|
The Department of Pharmacology was started in 1967 with the aim of research in basic and applied pharmacology of respiratory and allied diseases and to conduct research involving interactions between respiratory organs and regulatory substances, including drugs. The studies were also extended to clinical pharmacological/toxicological evaluation of various drugs and chemicals to which the respiratory tract was exposed. The Department actively conducting basic, applied and clinical research in the above mentioned areas with an aim to establish itself as an important clinical pharmacology and toxicology centre.
Major Activities and Achievements Research 1. Airway Smooth Muscle Pharmacology. 2. Visceral/Epithelial Transport of Water and Electrolytes. 3. Mechanisms of Osmoregulation. 4. Discovery of a new decapeptide (Pneumadin) which was the original work of this laboratory, which appears to be involved in disturbance of water/electrolyte balance which are common in lung diseases. Pharmacological and immunological studies are in progress in this area. 5. Studies on the toxicodynamic aspects of bronchodilators like methylxanthines. Neurotoxicological and cardiotoxicological studies and their mechanisms are in progress. Initial studies indicate the involvement of novel biological mechanisms for neurotoxicity which are amenable to pharmacotherapy, for neurotoxicity. This will help in identifying the viable antidote for methylxanthine toxicity. 6. Studies on the possible role of Nitric Oxide (NO) in respiratory and allied pathophysiology. NO is an important target molecule for NDDR for the new millennium and initial studies have revealed a potential role for NO in several aspects of respiratory and allied pharmacology/toxicology. 7. Influence of physiological factors like stress and hypoxia (which are important regulators of cardiorespiratory function) on immune regulation and its modulation by drugs. Teaching and Training Training is imparted to students for M.D. (Pharmacology) and Ph.D. (Pharmacology) degrees besides assisting in the teaching of M.D. (Respiratory diseases and Tuberculosis) and DTCD students of the faculty of medicine, Delhi University.Future Plans 1. To conduct basic, applied and clinical research in respiratory and allied disorders. The focus will be on an itegrated and inter disciplinary approach involving pharmacological and other techniques. 2. To develop the Department as an important Clinical Pharmacology and Toxicology center in the country. 3. To complete and extend the studies already going on in the Department involving different aspects of respiratory pharmacology & allied areas. |
|||||
|
© VPCI | All
rights reserved
|
